UPG Series
Adjustable Ultrasound for Precise Therapy
The UPG Series Ultrasound Pulse Generator creates adjustable power pulses in frequency, amplitude, pulse length, and PRF. It is used for non-invasive neuromodulation, targeted drug delivery, blood brain barrier opening, sonodynamic therapy, rehabilitation, thrombolysis, and other advanced research.
UPG Series
Adjustable Ultrasound for Precise Therapy
The UPG Series Ultrasound Pulse Generator creates adjustable power pulses in frequency, amplitude, pulse length, and PRF. It is used for non-invasive neuromodulation, targeted drug delivery, blood brain barrier opening, sonodynamic therapy, rehabilitation, thrombolysis, and other advanced research.
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Neuromodulation
Non-invasive ultrasound excites or inhibits neurons, regulating activity and circuit responses.
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BBB Modulation
Focused ultrasound temporarily opens the barrier to enhance drug delivery and therapeutic efficacy.
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Ultrasonic Thrombolysis
Employs ultrasound to dissolve blood clots for therapeutic purposes.
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HIFU Ablation
HIFU targets deep tissues non-invasively to destroy abnormal areas for therapeutic purposes.
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Sonodynamic Therapy
Focused ultrasound activates sonosensitizers in deep tissues non-invasively for anti-tumor effects.
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Non-Invasive Rehabilitation
Low-intensity ultrasound aids vascular growth, neural repair, and reduces inflammation.
- Q. Xian, Z. Qiu, S. Murugappan, S. Kala, K. F. Wong, D. Li, G. Li, Y. Jiang, Y. Wu, M. Su, X. Hou, J. Zhu, J. Guo, W. Qiu, and L. Sun*, Modulation of deep neural circuits with sonogenetics, PNAS, 120(22):e2220575120, May 2023.(IF:11.1)
- T. Wang, H. Zhang, W. Qiu, Y. Han, H. Liu, and Z. Li, Biomimetic nanoparticles directly remodel immunosuppressive microenvironment for boosting glioblastoma immunotherapy, Bioactive Materials, vol. 16, pp. 418-432, Oct 2022. (IF:18.9)
- Q. Xu, H. Zhang*, H. Liu, Y. Han, W. Qiu, Z. Li*, Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma, Biomaterials, 280:121287, Jan 2022. (IF: 12.479).
- H. Zhang, T. Wang, W. Qiu, Y. Han, Q. Sun, J. Zeng, F. Yan, H. Zheng, Z. Li*, and M. Gao, “Monitoring the Opening and Recovery of the Blood–Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultra-small Cu2–xSe Nanoparticles”, Nano Letters. vol. 18, no. 8, pp. 4985-4992, Jul. 2018. (IF: 12.279)
- [J. Ye, S. Tang, L. Meng], X. Li, X. Wen, S. Chen, L. Niu, X. Li, W. Qiu, H. Hu, M. Jiang, S. Shang, Q. Shu, H. Zheng*, S. Duan, and Y. Li*, “Ultrasonic control of neural activity through activation of the mechanosensitive channel MscL”, Nano Letters. vol. 18, no. 7, pp. 4148-4155, Jun. 2018. (IF: 12.279)
